EIF4E2 and EIF4ENIF1

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		EIF4E2	EIF4ENIF1
Description		eukaryotic translation initiation factor 4E family member 2	eukaryotic translation initiation factor 4E nuclear import factor 1
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GO Annotations	Cellular Component	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding
	Biological Process	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Protein Import Into Nucleus Negative Regulation Of Translation Stem Cell Population Maintenance Gene Silencing By RNA P-body Assembly Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation
Pathways		ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)	Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		45 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	27 interacting genes: ATXN1 CDK6 CFAP206 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 L3MBTL2 MGAT5B OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 SPAG5 TCHP TTC19 TXLNA USP2
Entrez ID		9470	56478
HPRD ID		05798	10456
Ensembl ID		ENSG00000135930	ENSG00000184708
Uniprot IDs		B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1	A0A024R1K0 Q9NRA8
PDB IDs		2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN	5ANR 6F9W 6X2R
Enriched GO Terms of Interacting Partners?
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