EIF4E2 and GIGYF1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, far western blotting, affinity chromatography technology)

		EIF4E2	GIGYF1
Description		eukaryotic translation initiation factor 4E family member 2	GRB10 interacting GYF protein 1
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex	Protein-containing Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Biological_process
Pathways		ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)	Autoimmune thyroid disease ( 32581359) LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		45 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	36 interacting genes: ANKRD10 ARMC7 ATN1 C1orf109 CBX8 CCDC57 CNOT9 CRACR2A DDX6 EIF4E2 ENKD1 FAM124B GRB10 GRB14 GRB7 KAT5 KIFC3 MCRS1 MNS1 NEK6 NFKBID PRKAA2 PRR35 RBM22 SCAF8 SCNM1 SMARCD1 SNRPA SNRPB SNRPC SPAG8 STAC3 TCEA2 TLE5 TROAP TSHZ2
Entrez ID		9470	64599
HPRD ID		05798	10145
Ensembl ID		ENSG00000135930	ENSG00000146830
Uniprot IDs		B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs		2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?