SNAP23 and STXBP5

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SNAP23	STXBP5
Description		synaptosome associated protein 23	syntaxin binding protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse	Cytoplasm Cytosol Plasma Membrane Acetylcholine-gated Channel Complex Synaptic Vesicle SNARE Complex Neuromuscular Junction Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Extrinsic Component Of Presynaptic Membrane Presynaptic Cytosol
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	GTPase Activator Activity Syntaxin-1 Binding Syntaxin Binding Myosin II Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion	Exocytosis Regulation Of Synaptic Vesicle Priming Protein Transport Regulation Of Exocytosis Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Regulation Of Protein Secretion Synaptic Vesicle Cycle Regulation Of Synaptic Vesicle Exocytosis
Pathways		ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bronchopulmonary dysplasia ( 23897914) Factor VIII levels ( 30586737) Low vWF levels ( 26486471) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Plasma plasminogen activator levels ( 24578379) Systolic blood pressure ( 30224653) Venous thromboembolism ( 31420334) vWF levels ( 20231535 30586737) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P	3 interacting genes: SNAP23 STX1A STX4
Entrez ID		8773	134957
HPRD ID		03962	06845
Ensembl ID		ENSG00000092531	ENSG00000164506
Uniprot IDs		A0A024R9R8 A8K287 O00161	Q5T5C0
PDB IDs		1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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