SNRPD3 and GEMIN5

Data Source:
HPRD (in vitro)

		SNRPD3	GEMIN5
Description		small nuclear ribonucleoprotein D3 polypeptide	gem nuclear organelle associated protein 5
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GO Annotations	Cellular Component	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Translation Regulation Of Translation Import Into Nucleus Protein-containing Complex Assembly
Pathways		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	snRNP Assembly
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Gamma glutamyl transferase levels ( 32084209)	Venous thromboembolism ( 32232851)
Interacting Genes		27 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 NTAQ1 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77	21 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2
Entrez ID		6634	25929
HPRD ID		03039	06109
Ensembl ID		ENSG00000100028	ENSG00000082516
Uniprot IDs		P62318	B7ZLC9 Q58EZ8 Q8TEQ6
PDB IDs		1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P	5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS
Enriched GO Terms of Interacting Partners?
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