SRP19 and TNPO1

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SRP19	TNPO1
Description		signal recognition particle 19	transportin 1
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GO Annotations	Cellular Component	Nucleolus Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Nucleus Cytoplasm Cytosol Cilium Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding	RNA Binding Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	Protein Import Into Nucleus Viral Process Intraciliary Transport Involved In Cilium Assembly Regulation Of MRNA Stability
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Factor VIII levels ( 30586737) Height ( 31562340) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean platelet volume ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 28957414) Serum albumin level ( 29403010) vWF levels ( 30586737)
Interacting Genes		8 interacting genes: APP IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1	18 interacting genes: ELAVL1 H2BC21 H3-4 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19 ULK2
Entrez ID		6728	3842
HPRD ID		01644	04210
Ensembl ID		ENSG00000153037	ENSG00000083312
Uniprot IDs		A0A087WYR0 A0A2U3TZN1 P09132	A0A024RAM0 Q92973
PDB IDs		1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73	1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ 4OO6 5J3V 5TQC 5YVG 5YVH 5YVI
Enriched GO Terms of Interacting Partners?
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