SPINT1 and TMEM190

Data Source:
BioGRID (two hybrid)

		SPINT1	TMEM190
Description		serine peptidase inhibitor, Kunitz type 1	transmembrane protein 190
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Exosome	Inner Acrosomal Membrane Nucleus Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Protein Binding Protein Self-association
	Biological Process	Neural Tube Closure Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Positive Regulation Of Glial Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Cellular Response To BMP Stimulus Negative Regulation Of Neural Precursor Cell Proliferation	Hematopoietic Progenitor Cell Differentiation
Pathways		MET Receptor Activation Signaling by MST1
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Blood protein levels ( 30072576 29875488)
Interacting Genes		23 interacting genes: ADAM33 AGR3 CLDN11 CLEC7A FAM3C HGFAC HMGB1 KRTAP1-3 MAL NLGN3 SLC38A7 SMCO4 ST14 TENT5A TF TMEM109 TMEM190 TMEM97 TSPAN33 UBQLN2 UBQLN4 UPK1B VAMP5	12 interacting genes: ARL13B CD69 CLDN5 CLEC2D KRTAP2-4 KRTAP5-11 KRTAP9-2 LDLRAD1 MACO1 MOB1A SPINT1 TEX29
Entrez ID		6692	147744
HPRD ID		05494	14373
Ensembl ID		ENSG00000166145	ENSG00000160472
Uniprot IDs		O43278	Q8WZ59
PDB IDs		1YC0 2MSX 4ISL 4ISN 4ISO 5EZD 5H7V
Enriched GO Terms of Interacting Partners?
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