TMEM190 and CLDN5

Data Source:
BioGRID (two hybrid)

		TMEM190	CLDN5
Description		transmembrane protein 190	claudin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Inner Acrosomal Membrane Nucleus Integral Component Of Membrane	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Tight Junction
	Molecular Function	Protein Binding Protein Self-association	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Blood-brain Barrier Negative Regulation Of Vascular Permeability Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier Regulation Of Bicellular Tight Junction Assembly
Pathways			Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)
Interacting Genes		12 interacting genes: ARL13B CD69 CLDN5 CLEC2D KRTAP2-4 KRTAP5-11 KRTAP9-2 LDLRAD1 MACO1 MOB1A SPINT1 TEX29	40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1
Entrez ID		147744	7122
HPRD ID		14373	03654
Ensembl ID		ENSG00000160472	ENSG00000184113
Uniprot IDs		Q8WZ59	D3DX19 O00501
PDB IDs
Enriched GO Terms of Interacting Partners?
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