TMEM190 and SPINT1

Data Source:
BioGRID (two hybrid)

		TMEM190	SPINT1
Description		transmembrane protein 190	serine peptidase inhibitor, Kunitz type 1
Image		No pdb structure
GO Annotations	Cellular Component	Inner Acrosomal Membrane Nucleus Integral Component Of Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Self-association	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation	Neural Tube Closure Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Positive Regulation Of Glial Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Cellular Response To BMP Stimulus Negative Regulation Of Neural Precursor Cell Proliferation
Pathways			MET Receptor Activation Signaling by MST1
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Blood protein levels ( 30072576) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		12 interacting genes: ARL13B CD69 CLDN5 CLEC2D KRTAP2-4 KRTAP5-11 KRTAP9-2 LDLRAD1 MACO1 MOB1A SPINT1 TEX29	23 interacting genes: ADAM33 AGR3 CLDN11 CLEC7A FAM3C HGFAC HMGB1 KRTAP1-3 MAL NLGN3 SLC38A7 SMCO4 ST14 TENT5A TF TMEM109 TMEM190 TMEM97 TSPAN33 UBQLN2 UBQLN4 UPK1B VAMP5
Entrez ID		147744	6692
HPRD ID		14373	05494
Ensembl ID		ENSG00000160472	ENSG00000166145
Uniprot IDs		Q8WZ59	O43278
PDB IDs			1YC0 2MSX 4ISL 4ISN 4ISO 5EZD 5H7V
Enriched GO Terms of Interacting Partners?
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