CAPN15 and RNF216

Data Source:
BioGRID (two hybrid)

		CAPN15	RNF216
Description		calpain 15	ring finger protein 216
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytosol Schaffer Collateral - CA1 Synapse Postsynaptic Endocytic Zone Glutamatergic Synapse
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Proteolysis	Apoptotic Process Viral Process Negative Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Defense Response To Virus By Host Protein K48-linked Ubiquitination Protein Catabolic Process, Modulating Synaptic Transmission
Pathways		Degradation of the extracellular matrix	Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		7 interacting genes: CPEB2 DAZAP2 RNF216 SOX4 TRAF2 UBC UBQLN2	30 interacting genes: AGFG1 BRCA1 CAPN15 FAM168A KIR2DL4 MAPK1 MORC3 OPTN RIPK1 RNF11 SUMO2 TLR3 TLR4 TLR5 TLR9 TNFAIP3 TRAF3 UBAC1 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L3 UBE2L6 USP5 YOD1 ZFAND2A
Entrez ID		6650	54476
HPRD ID		07220	15550
Ensembl ID		ENSG00000103326	ENSG00000011275
Uniprot IDs		O75808	A8K8N1 Q9NWF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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