RNF216 and ZFAND2A

Data Source:
BioGRID (two hybrid)

		RNF216	ZFAND2A
Description		ring finger protein 216	zinc finger AN1-type containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Schaffer Collateral - CA1 Synapse Postsynaptic Endocytic Zone Glutamatergic Synapse	Nucleus Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Apoptotic Process Viral Process Negative Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Defense Response To Virus By Host Protein K48-linked Ubiquitination Protein Catabolic Process, Modulating Synaptic Transmission
Pathways		Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) High light scatter reticulocyte percentage of red cells ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401)
Interacting Genes		30 interacting genes: AGFG1 BRCA1 CAPN15 FAM168A KIR2DL4 MAPK1 MORC3 OPTN RIPK1 RNF11 SUMO2 TLR3 TLR4 TLR5 TLR9 TNFAIP3 TRAF3 UBAC1 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L3 UBE2L6 USP5 YOD1 ZFAND2A	7 interacting genes: DAZAP2 LIG4 PLEKHB2 RNF216 RPL30 TRIM23 UBQLN2
Entrez ID		54476	90637
HPRD ID		15550	14277
Ensembl ID		ENSG00000011275	ENSG00000178381
Uniprot IDs		A8K8N1 Q9NWF9	Q8N6M9
PDB IDs
Enriched GO Terms of Interacting Partners?
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