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SMARCD1 and GATA1
Data Source:
BioGRID
(pull down)
SMARCD1
GATA1
Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
GATA binding protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
SWI/SNF Complex
Intracellular Membrane-bounded Organelle
NpBAF Complex
NBAF Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Transcription Repressor Complex
Protein-DNA Complex
Molecular Function
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Transcription Coactivator Activity
Signaling Receptor Binding
Protein Binding
Molecular Adaptor Activity
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
P53 Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
C2H2 Zinc Finger Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Transcription By RNA Polymerase II
Chromatin-mediated Maintenance Of Transcription
Cellular Response To Fatty Acid
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Regulation Of Transcription By RNA Polymerase II
Cell-cell Signaling
Blood Coagulation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Regulation Of Glycoprotein Biosynthetic Process
Regulation Of Definitive Erythrocyte Differentiation
Regulation Of Primitive Erythrocyte Differentiation
Erythrocyte Differentiation
Megakaryocyte Differentiation
Platelet Formation
Basophil Differentiation
Eosinophil Differentiation
Negative Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Proliferation
Embryonic Hemopoiesis
Eosinophil Fate Commitment
Negative Regulation Of Apoptotic Process
Cell Fate Commitment
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Erythrocyte Development
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Platelet Aggregation
Transcriptional Activation By Promoter-enhancer Looping
Dendritic Cell Differentiation
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
Congenital dyserythropoietic anemias (CDAs)
GWAS
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
156 interacting genes:
ABI1
ABI2
ABI3
ADAT2
ANKRD23
ANKRD49
ANKS1A
ANP32B
APOA5
AR
ARMC10
ARRDC3
BCAS2
BEND5
BEX3
BHLHB9
BLOC1S5
BRWD1
C19orf54
C1orf109
C4BPA
CALCOCO2
CCDC102B
CCDC130
CCDC197
CCDC33
CCDC85B
CDC5L
CDR2
CDSN
CDX2
CEACAM6
CHFR
CHN2
CLNK
COG6
COL1A2
CORO1A
CUEDC1
CYSRT1
DCTN2
DISC1
EGFL7
EIF4G1
ESR1
ESS2
FAM136A
FAM161A
FBXO7
FEZ1
FOS
FUS
GATA1
GCC1
GIGYF1
GINS3
GOLGA6L9
GRAMD4
HES6
HNRNPC
HOMEZ
HOXD3
HSF2BP
HSPB1
IGKC
IKBIP
IKZF3
INSC
IQCB1
JUN
KATNBL1
KDM1A
KEAP1
KIAA0753
KLF1
KMT5B
KRT15
KRT16
KRT18
KRT27
KRT31
KRT34
KRT37
KRT38
KRT75
LDB2
LDOC1
LZTS2
MAGEA2
MAGEA2B
MAGEA6
MED4
MKRN3
MTNR1B
MTUS2
NAB2
NECAB2
NELFA
NME1
NONO
NR1H4
NR3C1
NUCB2
NUDT16L1
NUTM1
PACSIN3
PAICS
PBX4
PCBD1
PGR
PICK1
PIH1D1
PKNOX2
PLAGL2
PPM1J
PRDX1
PRMT6
PSTPIP1
RIF1
RORB
RPS29
SCARA5
SCHIP1
SCNM1
SERTAD3
SHISA6
SMARCB1
SMUG1
SNF8
SPSB2
STH
STMN3
SYCE1L
TCP10L
THOC7
TLE5
TNIP2
TP53
TRIM27
TRIM54
TRIM72
USHBP1
USP54
VPS37B
WASHC1
WWP2
YWHAG
ZC2HC1C
ZMAT5
ZMYND12
ZNF417
ZNF438
ZNF511
ZNF629
ZNF655
ZNF69
85 interacting genes:
AKT1
ARID1A
ARMC7
ATP6V0D1
BCL6
CASP3
CCDC24
CEBPE
CHRD
CREBBP
DGCR6L
DNMT3L
FANCG
FANCL
FBF1
FHL3
FLI1
FRS3
GLRX3
GOLGA2
GRAP2
HDAC3
HDAC4
HDAC5
HEMGN
HEXIM2
HEY1
HOXA1
HSPA4
KANK2
KRTAP10-5
KRTAP3-2
KRTAP4-11
KRTAP4-5
KRTAP9-2
LMO2
LZTS2
MAPK1
MAPK3
MAPK6
MDFI
MED1
MGAT5B
MKRN3
PITX1
PLSCR4
PML
PNMA1
PPP1R16B
PRKAA1
PRKAB2
PSMF1
RADIL
RAI1
RBPMS
RIN3
SMARCA4
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SMARCE1
SP1
SPI1
SPIB
SRA1
STAT3
TAF7
TAL1
TAX1BP3
TEKT4
TLE5
TNS2
TRAF1
TRIM25
TRIM29
TRIP6
USP7
ZBTB16
ZBTB22
ZDHHC17
ZFPM1
ZFPM2
ZNF521
ZZZ3
Entrez ID
6602
2623
HPRD ID
03438
02372
Ensembl ID
ENSG00000066117
ENSG00000102145
Uniprot IDs
Q96GM5
P15976
PDB IDs
6LTH
6LTJ
6G0Q
Enriched GO Terms of Interacting Partners
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