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FUNDC2 and FCER1G
Data Source:
BioGRID
(two hybrid)
FUNDC2
FCER1G
Description
FUN14 domain containing 2
Fc fragment of IgE receptor Ig
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Integral Component Of Mitochondrial Outer Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
Protein Binding
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
Biological Process
Autophagy Of Mitochondrion
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
Drugs
Benzylpenicilloyl polylysine
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Interacting Genes
37 interacting genes:
AQP6
ARL13B
ARL15
ASCC2
ATP13A2
CD79A
CIDEB
COX20
CRB3
CYB5R3
EBP
EIF6
EVI2B
FCER1G
FGF14
GPR152
KCNJ6
KIR2DL3
MFSD14B
MGST3
NACA
NSF
NUDT21
REEP4
RETREG3
RGS1
SAT1
SDR16C5
SLC10A6
SLC16A10
SLC66A2
STOM
SYT2
TMEM154
TMX2
TP53I3
USP13
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
Entrez ID
65991
2207
HPRD ID
06586
00916
Ensembl ID
ENSG00000165775
ENSG00000158869
Uniprot IDs
Q9BWH2
P30273
PDB IDs
Enriched GO Terms of Interacting Partners
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