FUNDC2 and RGS1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FUNDC2	RGS1
Description		FUN14 domain containing 2	regulator of G protein signaling 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane	Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding
	Biological Process	Autophagy Of Mitochondrion	Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Bacterium Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Leukotriene Signaling Pathway
Pathways			G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS			Celiac disease ( 22057235 20190752 30572963 18311140) Multiple sclerosis ( 24076602 21833088 27386562) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		37 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 EBP EIF6 EVI2B FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MFSD14B MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 STOM SYT2 TMEM154 TMX2 TP53I3 USP13	9 interacting genes: APP FBXO7 FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A
Entrez ID		65991	5996
HPRD ID		06586	15968
Ensembl ID		ENSG00000165775	ENSG00000090104
Uniprot IDs		Q9BWH2	Q08116
PDB IDs			2BV1 2GTP
Enriched GO Terms of Interacting Partners?
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