SMARCC1 and GSTO2

Data Source:
BioGRID (two hybrid)

		SMARCC1	GSTO2
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	glutathione S-transferase omega 2
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GO Annotations	Cellular Component	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Cytosol Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Glutathione Metabolic Process Xenobiotic Metabolic Process L-ascorbic Acid Metabolic Process Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Glutathione conjugation Vitamin C (ascorbate) metabolism
Drugs			Glutathione
Diseases
GWAS		Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)
Interacting Genes		53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581	10 interacting genes: GCA HOXC8 INCA1 KLHL10 NTAQ1 PFDN5 POLR1C PWWP3A SMARCC1 TFAP2A
Entrez ID		6599	119391
HPRD ID		03435	13614
Ensembl ID		ENSG00000173473	ENSG00000065621
Uniprot IDs		Q58EY4 Q92922	Q9H4Y5
PDB IDs		2YUS 5GJK 6KZ7	3Q18 3Q19 3QAG
Enriched GO Terms of Interacting Partners?
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