GSTO2 and HOXC8

Data Source:
BioGRID (two hybrid)

		GSTO2	HOXC8
Description		glutathione S-transferase omega 2	homeobox C8
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Microtubule Cytoskeleton
	Molecular Function	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process L-ascorbic Acid Metabolic Process Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development
Pathways		Glutathione conjugation Vitamin C (ascorbate) metabolism
Drugs		Glutathione
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: GCA HOXC8 INCA1 KLHL10 NTAQ1 PFDN5 POLR1C PWWP3A SMARCC1 TFAP2A	107 interacting genes: ADAMTSL4 ANKS1A BLZF1 BMPR1A BTG2 C11orf1 C19orf54 C1orf109 CADPS CCM2 CEP70 CRYBA1 CYSRT1 DLX2 DLX5 DVL3 DZIP3 ECM1 FNTB GMNN GOLGA6L9 GSTO2 GYS1 HESX1 HOMEZ HOXD3 HSF2BP IKZF3 JUN KCTD9 KHDC1 KPRP KRT34 KRT35 KRT36 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-3 KRTAP19-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LDLRAP1 LDOC1 LHX2 LHX3 LRP2BP MAPK8IP2 MEOX1 MEOX2 METTL15 MGAT5B MSX1 NADSYN1 NBPF19 NFKBID NID2 NOTCH2NLA OIP5 PAX5 PAX6 PAX8 PBX1 PBX2 PBX4 PDE4DIP PFDN5 PLA2G10 PLEKHG4 POU2AF1 POU6F2 PPARA PRDM14 PRDM6 RBCK1 RBPMS SLAIN1 SMAD1 SMAD4 SMAD6 SNX17 TBC1D1 TBX19 TBX22 TEKT4 TLE5 TNS2 TRAF1 TRIB3 TRIM27 TRIM42 TRIP6 TSC1 USP54 VENTX WWOX ZFP90 ZMAT5 ZNF34 ZRANB1
Entrez ID		119391	3224
HPRD ID		13614	00856
Ensembl ID		ENSG00000065621	ENSG00000037965
Uniprot IDs		Q9H4Y5	P31273
PDB IDs		3Q18 3Q19 3QAG
Enriched GO Terms of Interacting Partners?
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