GSTO2 and SMARCC1

Data Source:
BioGRID (two hybrid)

		GSTO2	SMARCC1
Description		glutathione S-transferase omega 2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process L-ascorbic Acid Metabolic Process Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Glutathione conjugation Vitamin C (ascorbate) metabolism	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Glutathione
Diseases
GWAS			Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)
Interacting Genes		10 interacting genes: GCA HOXC8 INCA1 KLHL10 NTAQ1 PFDN5 POLR1C PWWP3A SMARCC1 TFAP2A	53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581
Entrez ID		119391	6599
HPRD ID		13614	03435
Ensembl ID		ENSG00000065621	ENSG00000173473
Uniprot IDs		Q9H4Y5	Q58EY4 Q92922
PDB IDs		3Q18 3Q19 3QAG	2YUS 5GJK 6KZ7
Enriched GO Terms of Interacting Partners?
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