Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SMARCB1 and LZTS2
Data Source:
BioGRID
(two hybrid)
SMARCB1
LZTS2
Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
leucine zipper tumor suppressor 2
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromosome
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
SWI/SNF Complex
Protein-containing Complex
Brahma Complex
Intracellular Membrane-bounded Organelle
NpBAF Complex
NBAF Complex
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Molecular Function
RNA Polymerase I Core Promoter Sequence-specific DNA Binding
P53 Binding
DNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Protein Binding
Tat Protein Binding
Nucleosomal DNA Binding
Protein Binding
Biological Process
RNA Polymerase I Preinitiation Complex Assembly
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Nervous System Development
DNA Integration
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
ATP-dependent Chromatin Remodeling
Positive Regulation By Host Of Viral Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K9 Dimethylation
Negative Regulation Of Histone H3-K9 Trimethylation
Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Positive Regulation Of Glucose Mediated Signaling Pathway
Positive Regulation Of Histone H3-K9 Acetylation
Regulation Of Histone H4-K16 Acetylation
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Fractional shortening (
29403010
)
IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) (
28878392
)
IgG digalactosylation phenotypes (multivariate analysis) (
28878392
)
IgG disialylation phenotypes (multivariate analysis) (
28878392
)
IgG fucosylation phenotypes (multivariate analysis) (
28878392
)
IgG galactosylation phenotypes (multivariate analysis) (
28878392
)
IgG glycosylation (
23382691
)
IgG monogalactosylation phenotypes (multivariate analysis) (
28878392
)
IgG N-glycosylation phenotypes (multivariate analysis) (
28878392
32128391
)
IgG sialylation phenotypes (multivariate analysis) (
28878392
)
N-glycan levels (
31163085
)
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Interacting Genes
112 interacting genes:
ABI2
AKT1
APP
ARL11
ATP5F1A
BCL2L11
BHLHE40
BLZF1
CALR
CAMK2D
CCDC120
CCDC33
CD69
CDC23
CDX2
CEBPB
CHFR
CXCL11
CYB5D2
DNAJA3
DPH6
FAM90A1
FAM9B
FUS
GADD45G
GATA1
GFAP
GOLGA2
HGS
HNRNPM
HOMEZ
HOOK2
HSF2BP
HSFY1
IHO1
IKZF3
IL16
KCTD9
KLC3
KLF1
KMT2B
KMT2C
KPNA6
KRT15
KRT19
KRT6A
KRT6B
KRT6C
LDOC1
LENG8
LNX2
LY96
LZTS2
MAP1LC3B
MAP3K20
MAPK8IP2
MBIP
MCPH1
MECP2
MESD
MIF4GD
MRPL53
MXI1
MYC
NCK2
NONO
NR0B2
NR3C1
OSGIN1
OTX2
PDPK1
PICK1
PPP1CC
PPP1R15A
PRKAB2
PRMT5
PSMB1
RAN
RB1
RELB
RINT1
RPN1
RPS6KA5
RUSC1
RXRA
SAXO1
SIN3B
SMARCA4
SMARCC2
SMARCD1
SRC
TACC2
TAF1D
TASOR2
TEKT5
TFIP11
TLE5
TNFAIP1
TNRC6A
TP53
TRIM14
TRIM27
TRIM35
TSC22D4
UBQLN4
VIM
XPO1
YEATS4
ZC3H11A
ZDHHC17
ZNF398
ZNF688
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
Entrez ID
6598
84445
HPRD ID
03364
14341
Ensembl ID
ENSG00000099956
ENSG00000107816
Uniprot IDs
G5E975
Q12824
Q9H836
B4DP66
Q9BRK4
PDB IDs
5AJ1
5GJK
5L7A
5L7B
6AX5
6KAG
6KZ7
6LTH
6LTJ
6UCH
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?