Description |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
MYC proto-oncogene, bHLH transcription factor |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
- Amyotrophic lateral sclerosis (sporadic) ( 24529757)
- Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
- Asthma (childhood onset) ( 27611488)
- Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
- Brain morphology (MOSTest) ( 32665545)
- Lead levels ( 26025379)
- Lung function (FEV1) ( 30061609)
- Lung function (FVC) ( 30061609)
- Monobrow ( 27182965)
- Neuritic plaque ( 31497858)
- Nose size ( 27182965)
- Parkinson's disease ( 26227905)
- Superior frontal gyrus grey matter volume ( 25335168)
- Systolic blood pressure ( 26969751)
- Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
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Interacting Genes |
27 interacting genes:
ACTL6A
ACTL6B
AR
ARID1B
BEND7
BRCA1
CEBPA
ESR1
H3C1
HSPB1
KHDRBS1
MDM2
MDM4
MECP2
MYB
MYC
NR0B2
NR3C1
NR4A2
PHB
PITX1
PRMT5
PRPF6
RAP1A
SDCBP
SIN3B
SS18
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178 interacting genes:
ACTL6A
AKT1
APP
ARAF
ARNT
ATAD2
AURKA
AXIN1
BCL2
BIN1
BRCA1
BRD3
BTRC
CALM1
CBLC
CCAR2
CCNE1
CCNT1
CDC6
CDC73
CDCA7L
CDK1
CDK4
CDK6
CDK8
CDK9
CDKN1B
CDKN2A
CDKN2B
CDKN2C
CEBPA
CEBPB
CEP57
CIP2A
CREBBP
CSNK2A1
CSNK2A2
DACH1
DNMT3A
EFNB1
ELF3
EP300
EP400
EPHA2
ERBB2
FBXO8
FBXW7
FBXW8
FGFR4
FZR1
GCN1
GLIS1
GLIS2
GPX2
GRM1
GSK3A
GSK3B
GTF2F1
GTF2F2
GTF2I
HGF
HIF1A
HSP90AA1
ING4
KAT2A
KAT2B
KAT5
KDELR2
KDM1A
KIDINS220
LATS2
LDOC1
MAP2K1
MAP2K5
MAPK1
MAPK14
MAPK3
MAPK7
MAPK8
MAX
MDM2
MED1
MED16
MEN1
MET
MLH1
MOK
MSH2
MXD1
MXI1
MYCBP
MYCBP2
NDRG1
NEK11
NF2
NFIC
NFYB
NFYC
NMI
NONO
NOTCH3
NSD3
NUCB1
PAK2
PARP10
PDGFRA
PFDN5
PIK3CA
PLAU
PLK1
PML
PPP2CA
PRDX1
PSMC3
PTEN
RAF1
RASSF1
RB1
RBL1
RELA
RIOX2
RUVBL1
RUVBL2
SAP130
SENP2
SF3B1
SKP1
SKP2
SMAD2
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SNIP1
SNRNP70
SOX3
SOX4
SP1
SPAG9
STK11
SUPT3H
TADA2A
TAF12
TAF1B
TAF9
TBP
TEAD2
TERT
TFAP2A
TFAP2B
TIAM1
TONSL
TP53
TP73
TRIM55
TRIM6
TRIM63
TRRAP
TSC1
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
UBB
USP2
USP22
USP36
USP37
USP7
VDR
WT1
YAF2
YBX1
YY1
ZBTB17
ZNF281
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Entrez ID |
6595 |
4609 |
HPRD ID |
02483 |
01818 |
Ensembl ID |
ENSG00000080503
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ENSG00000136997
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Uniprot IDs |
B1ALF6
B4DNT1
B4DSC8
F6T8Q0
F6VDE0
P51531
Q56A76
Q8N9Q1
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P01106
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PDB IDs |
2DAT
4QY4
5DKC
5DKH
6EG2
6EG3
6HAX
6HAY
6HAZ
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1A93
1EE4
1MV0
1NKP
2A93
2OR9
4Y7R
5I4Z
5I50
6C4U
6E16
6E24
6G6J
6G6K
6G6L
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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