SMARCA2 and NR4A2

  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

SMARCA2

NR4A2

Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 nuclear receptor subfamily 4 group A member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma (childhood onset) ( 27611488)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Brain morphology (MOSTest) ( 32665545)
  • Lead levels ( 26025379)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Monobrow ( 27182965)
  • Neuritic plaque ( 31497858)
  • Nose size ( 27182965)
  • Parkinson's disease ( 26227905)
  • Superior frontal gyrus grey matter volume ( 25335168)
  • Systolic blood pressure ( 26969751)
  • Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
  • Age at voice drop ( 27182965)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Depression ( 29700475)
  • HDL cholesterol levels ( 32109663)
  • Leisure-time exercise behaviour ( 30102679)
  • Leisure-time exercise behaviour (age-stratified) ( 30102679)
  • Lung function (FEV1/FVC) ( 30061609)
  • Menarche (age at onset) ( 21102462 25231870)
  • Response to statin therapy ( 20339536)
Interacting Genes 27 interacting genes: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA ESR1 H3C1 HSPB1 KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 RAP1A SDCBP SIN3B SS18 15 interacting genes: BAZ1B CDKN1C CDKN2D COPS5 MAPK1 ODAD2 PIAS4 PPARG RPS6KA1 RXRA RXRB SMARCA2 SMARCA4 TCEAL5 VHL
Entrez ID 6595 4929
HPRD ID 02483 03493
Ensembl ID ENSG00000080503 ENSG00000153234
Uniprot IDs B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1 F1D8N6 F1DAL2 P43354 Q53EL4
PDB IDs 2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ 1OVL 5Y41 5YD6 6DDA 6L6L 6L6Q
Enriched GO Terms of Interacting Partners?
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