SMARCA2 and SS18

  • Data Source:
  • HPRD (in vitro, in vivo)

SMARCA2

SS18

Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SS18 subunit of BAF chromatin remodeling complex
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma (childhood onset) ( 27611488)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Brain morphology (MOSTest) ( 32665545)
  • Lead levels ( 26025379)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Monobrow ( 27182965)
  • Neuritic plaque ( 31497858)
  • Nose size ( 27182965)
  • Parkinson's disease ( 26227905)
  • Superior frontal gyrus grey matter volume ( 25335168)
  • Systolic blood pressure ( 26969751)
  • Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
  • Autoimmune thyroid disease ( 32581359)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Mean corpuscular hemoglobin ( 32888494)
  • Nickel levels ( 26025379)
  • Obesity-related traits ( 23251661)
  • Periodontitis (Mean PAL) ( 24024966)
  • QT interval (sulfonylurea treatment interaction) ( 27958378)
  • Rhegmatogenous retinal detachment ( 23585552)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Toenail selenium levels ( 25343990)
Interacting Genes 27 interacting genes: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA ESR1 H3C1 HSPB1 KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 RAP1A SDCBP SIN3B SS18 9 interacting genes: EP300 FUS GRB2 H3-3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4
Entrez ID 6595 6760
HPRD ID 02483 02559
Ensembl ID ENSG00000080503 ENSG00000141380
Uniprot IDs B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1 A0A024RC40 B4DLD3 B4DR34 B4E2J6 Q15532 Q4VAX0
PDB IDs 2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ
Enriched GO Terms of Interacting Partners?
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