Description |
MYC proto-oncogene, bHLH transcription factor |
fibroblast growth factor receptor 4 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Activated partial thromboplastin time ( 22703881)
- Apolipoprotein A1 levels ( 32203549)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Circulating fibroblast growth factor 23 levels ( 30217807)
- Height ( 28552196 25282103 31562340)
- Hemoglobin levels ( 32327693)
- Hip shape (DXA scan) ( 30320955)
- Narrowest width of the femoral neck ( 30888730)
- Nonsyndromic cleft lip ( 31609978)
- Type 2 diabetes ( 32499647 30718926)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for BMI in smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412)
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Interacting Genes |
178 interacting genes:
ACTL6A
AKT1
APP
ARAF
ARNT
ATAD2
AURKA
AXIN1
BCL2
BIN1
BRCA1
BRD3
BTRC
CALM1
CBLC
CCAR2
CCNE1
CCNT1
CDC6
CDC73
CDCA7L
CDK1
CDK4
CDK6
CDK8
CDK9
CDKN1B
CDKN2A
CDKN2B
CDKN2C
CEBPA
CEBPB
CEP57
CIP2A
CREBBP
CSNK2A1
CSNK2A2
DACH1
DNMT3A
EFNB1
ELF3
EP300
EP400
EPHA2
ERBB2
FBXO8
FBXW7
FBXW8
FGFR4
FZR1
GCN1
GLIS1
GLIS2
GPX2
GRM1
GSK3A
GSK3B
GTF2F1
GTF2F2
GTF2I
HGF
HIF1A
HSP90AA1
ING4
KAT2A
KAT2B
KAT5
KDELR2
KDM1A
KIDINS220
LATS2
LDOC1
MAP2K1
MAP2K5
MAPK1
MAPK14
MAPK3
MAPK7
MAPK8
MAX
MDM2
MED1
MED16
MEN1
MET
MLH1
MOK
MSH2
MXD1
MXI1
MYCBP
MYCBP2
NDRG1
NEK11
NF2
NFIC
NFYB
NFYC
NMI
NONO
NOTCH3
NSD3
NUCB1
PAK2
PARP10
PDGFRA
PFDN5
PIK3CA
PLAU
PLK1
PML
PPP2CA
PRDX1
PSMC3
PTEN
RAF1
RASSF1
RB1
RBL1
RELA
RIOX2
RUVBL1
RUVBL2
SAP130
SENP2
SF3B1
SKP1
SKP2
SMAD2
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SNIP1
SNRNP70
SOX3
SOX4
SP1
SPAG9
STK11
SUPT3H
TADA2A
TAF12
TAF1B
TAF9
TBP
TEAD2
TERT
TFAP2A
TFAP2B
TIAM1
TONSL
TP53
TP73
TRIM55
TRIM6
TRIM63
TRRAP
TSC1
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
UBB
USP2
USP22
USP36
USP37
USP7
VDR
WT1
YAF2
YBX1
YY1
ZBTB17
ZNF281
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83 interacting genes:
ABCB5
AKT1
ANGPTL4
ARAF
ARNT
BECN1
BLID
CASC3
CBLC
CCND2
CCNE1
CD44
CDH2
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
DIRAS3
EPHA2
EPHA4
EPSTI1
ERBB2
ERRFI1
FGF1
FGF17
FGF18
FGF19
FGF2
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FZR1
GLCE
GLIS2
GRM1
HGF
HIF1A
IGF1R
KDELR2
LATS2
LRATD2
MAP2K5
MAP2K6
MAP3K5
MAPK14
MDM4
MET
MSH2
MTA3
MYC
NF2
NSD3
OSGIN1
PDGFRA
PDLIM2
PLCG1
PPP3CA
PSMC3IP
PTPN11
PTPN12
PTPN6
PTPRR
RAF1
RASL10B
RASSF1
RNF20
ROS1
SCGB3A1
STAT1
STAT3
STK11
TEAD2
TERT
THRSP
TP53
TSC1
TTYH2
WIF1
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Entrez ID |
4609 |
2264 |
HPRD ID |
01818 |
00625 |
Ensembl ID |
ENSG00000136997
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ENSG00000160867
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Uniprot IDs |
P01106
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B4DVP5
J3KPQ0
P22455
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PDB IDs |
1A93
1EE4
1MV0
1NKP
2A93
2OR9
4Y7R
5I4Z
5I50
6C4U
6E16
6E24
6G6J
6G6K
6G6L
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1QCT
4QQ5
4QQC
4QQJ
4QQT
4QRC
4R6V
4TYE
4TYG
4TYI
4TYJ
4UXQ
4XCU
5JKG
5NUD
5NWZ
5XFF
5XFJ
6IUO
6IUP
6J6Y
6JPE
6JPJ
6NVG
6NVH
6NVI
6NVJ
6NVK
6V9C
6YI8
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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