SLC12A4 and AP3M1

Data Source:
BioGRID (two hybrid)

		SLC12A4	AP3M1
Description		solute carrier family 12 member 4	adaptor related protein complex 3 subunit mu 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Synapse	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Protein Binding Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding	Protein Binding Small GTPase Binding
	Biological Process	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Cation-coupled Chloride cotransporters	Association of TriC/CCT with target proteins during biosynthesis
Drugs		Potassium chloride Bumetanide
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: AP3M1 ATF7IP CNFN CYSRT1 KRTAP12-2 KRTAP19-2 MB21D2 MTNR1B TMEM102 ZNF655	15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9
Entrez ID		6560	26985
HPRD ID		04987	16496
Ensembl ID		ENSG00000124067	ENSG00000185009
Uniprot IDs		B4DF30 Q9UP95	A0A024QZR5 B4DRN6 Q9Y2T2
PDB IDs		6KKR 6KKT 6KKU
Enriched GO Terms of Interacting Partners?
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