SLC9A3 and CHP2

Data Source:
HPRD (in vivo, in vitro)

		SLC9A3	CHP2
Description		solute carrier family 9 member A3	calcineurin like EF-hand protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Cell Surface Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity PDZ Domain Binding	Calcium Ion Binding Protein Binding
	Biological Process	Ion Transport Regulation Of Intracellular PH Potassium Ion Transmembrane Transport Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion
Pathways		Sodium/Proton exchangers
Drugs		Tenapanor
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Estimated glomerular filtration rate ( 31152163) Lung disease severity in cystic fibrosis ( 26417704) Ulcerative colitis ( 28067908 23128233)
Interacting Genes		8 interacting genes: CHP1 CHP2 LRP2 MAST2 PDZK1 SHANK2 SLC9A3R1 SLC9A3R2	6 interacting genes: MDFI SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5
Entrez ID		6550	63928
HPRD ID		01660	14259
Ensembl ID		ENSG00000066230	ENSG00000166869
Uniprot IDs		P48764	O43745
PDB IDs			2BEC
Enriched GO Terms of Interacting Partners?
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