Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SFTPA1 and PRDX6
Data Source:
BioGRID
(pull down)
SFTPA1
PRDX6
Description
surfactant protein A1
peroxiredoxin 6
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Extracellular Space
Multivesicular Body
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum
Lamellar Body
Clathrin-coated Endocytic Vesicle
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Membrane
Azurophil Granule Lumen
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Lipid Transporter Activity
Protein Binding
Carbohydrate Binding
Glutathione Peroxidase Activity
Phospholipase A2 Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Cadherin Binding
1-acylglycerophosphocholine O-acyltransferase Activity
Calcium-independent Phospholipase A2 Activity
Peroxiredoxin Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
Toll-like Receptor Signaling Pathway
Lipid Transport
Respiratory Gaseous Exchange By Respiratory System
Opsonization
Cellular Protein Metabolic Process
Response To Oxidative Stress
Cellular Response To Oxidative Stress
Hydrogen Peroxide Catabolic Process
Neutrophil Degranulation
Cell Redox Homeostasis
Glycerophospholipid Catabolic Process
Positive Regulation Of MRNA Splicing, Via Spliceosome
Cellular Oxidant Detoxification
Pathways
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Signal regulatory protein family interactions
Surfactant metabolism
Regulation of TLR by endogenous ligand
Defective CSF2RB causes SMDP5
Defective CSF2RA causes SMDP4
Detoxification of Reactive Oxygen Species
Neutrophil degranulation
Drugs
2-(N-morpholino)ethanesulfonic acid
2-(N-morpholino)ethanesulfonic acid
Copper
Diseases
GWAS
Adult body size (
32376654
)
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Blood protein levels (
30072576
)
Systemic lupus erythematosus (
26663301
)
Systemic sclerosis (
31672989
)
Interacting Genes
2 interacting genes:
DMBT1
PRDX6
21 interacting genes:
CASP10
CASP8
GPX4
GSTP1
HNF4G
MAPK1
NCF2
NR4A1
ORM2
PAXIP1
PPARD
PSMD8
RARA
SFTPA1
STH
SUMO2
SUMO4
TERF1
TERF2IP
UCHL5
YWHAE
Entrez ID
653509
9588
HPRD ID
19256
03817
Ensembl ID
ENSG00000122852
ENSG00000117592
Uniprot IDs
A0A024QZP2
B4DNP6
Q8IWL2
P30041
V9HWC7
PDB IDs
1PRX
5B6M
5B6N
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?