SFTPA1 and DMBT1

Data Source:
BioGRID (pull down, pull down)

		SFTPA1	DMBT1
Description		surfactant protein A1	deleted in malignant brain tumors 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lamellar Body Clathrin-coated Endocytic Vesicle	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome
	Molecular Function	Lipid Transporter Activity Protein Binding Carbohydrate Binding	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Extracellular Matrix Binding
	Biological Process	Toll-like Receptor Signaling Pathway Lipid Transport Respiratory Gaseous Exchange By Respiratory System Opsonization Cellular Protein Metabolic Process	Endocytosis Defense Response Multicellular Organism Development Protein Transport Viral Process Epithelial Cell Differentiation Detection Of Bacterial Lipoprotein Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus
Pathways		Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4	Surfactant metabolism
Drugs		2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS			Iris heterochromicity ( 30895295)
Interacting Genes		2 interacting genes: DMBT1 PRDX6	2 interacting genes: SFTPA1 SFTPD
Entrez ID		653509	1755
HPRD ID		19256	03575
Ensembl ID		ENSG00000122852	ENSG00000187908
Uniprot IDs		A0A024QZP2 B4DNP6 Q8IWL2	A0A590UJ76 Q9UGM3
PDB IDs			6SA4 6SA5 6SAN
Enriched GO Terms of Interacting Partners?
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