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SFTPA1

Description surfactant protein A1
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Collagen Trimer
  • Extracellular Space
  • Multivesicular Body
  • Endoplasmic Reticulum Membrane
  • Rough Endoplasmic Reticulum
  • Lamellar Body
  • Clathrin-coated Endocytic Vesicle
Molecular Function
  • Lipid Transporter Activity
  • Protein Binding
  • Carbohydrate Binding
Biological Process
  • Toll-like Receptor Signaling Pathway
  • Lipid Transport
  • Respiratory Gaseous Exchange By Respiratory System
  • Opsonization
  • Cellular Protein Metabolic Process
Pathways
  • Toll Like Receptor 4 (TLR4) Cascade
  • Toll Like Receptor TLR1:TLR2 Cascade
  • Signal regulatory protein family interactions
  • Surfactant metabolism
  • Regulation of TLR by endogenous ligand
  • Defective CSF2RB causes SMDP5
  • Defective CSF2RA causes SMDP4
Drugs
  • 2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS
Novel Interacting Genes 1 novel interacting genes: SFTPD
Interacting Genes 2 interacting genes: DMBT1 PRDX6
Entrez ID 653509
HPRD ID 19256
Ensembl ID ENSG00000122852
Uniprot IDs A0A024QZP2 B4DNP6 Q8IWL2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025