DMBT1 and SFTPD

Data Source:
BioGRID (biochemical, pull down, pull down)
HPRD (in vitro)

		DMBT1	SFTPD
Description		deleted in malignant brain tumors 1	surfactant protein D
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome	Extracellular Region Collagen Trimer Extracellular Space Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endocytic Vesicle Clathrin-coated Endocytic Vesicle
	Molecular Function	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Extracellular Matrix Binding	Protein Binding Carbohydrate Binding
	Biological Process	Endocytosis Defense Response Multicellular Organism Development Protein Transport Viral Process Epithelial Cell Differentiation Detection Of Bacterial Lipoprotein Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus	Regulation Of Cytokine Production Toll-like Receptor Signaling Pathway Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Regulation Of Immune Response Negative Regulation By Host Of Symbiont Molecular Function Reactive Oxygen Species Metabolic Process Regulation Of Adhesion Of Symbiont To Host Epithelial Cell
Pathways		Surfactant metabolism	Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs			Beta-D-Glucose
Diseases
GWAS		Iris heterochromicity ( 30895295)	Chronic obstructive pulmonary disease ( 28166215 30804561) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		2 interacting genes: SFTPA1 SFTPD	3 interacting genes: DCN DMBT1 MFAP4
Entrez ID		1755	6441
HPRD ID		03575	01522
Ensembl ID		ENSG00000187908	ENSG00000133661
Uniprot IDs		A0A590UJ76 Q9UGM3	P35247
PDB IDs		6SA4 6SA5 6SAN	1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?
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