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SLC3A2 and SLC7A8
Data Source:
HPRD
(in vitro)
SLC3A2
SLC7A8
Description
solute carrier family 3 member 2
solute carrier family 7 member 8
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Lysosomal Membrane
Plasma Membrane
Basal Plasma Membrane
Cell Surface
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Cell Junction
Melanosome
Extracellular Exosome
Amino Acid Transport Complex
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Microvillus Membrane
Molecular Function
RNA Binding
Double-stranded RNA Binding
Catalytic Activity
Calcium:sodium Antiporter Activity
Protein Binding
Aromatic Amino Acid Transmembrane Transporter Activity
Neutral Amino Acid Transmembrane Transporter Activity
L-alanine Transmembrane Transporter Activity
L-leucine Transmembrane Transporter Activity
Cadherin Binding
Protein Binding
Organic Cation Transmembrane Transporter Activity
Amino Acid Transmembrane Transporter Activity
Neutral Amino Acid Transmembrane Transporter Activity
L-amino Acid Transmembrane Transporter Activity
L-alanine Transmembrane Transporter Activity
Glycine Transmembrane Transporter Activity
L-leucine Transmembrane Transporter Activity
Thyroid Hormone Transmembrane Transporter Activity
Toxin Transmembrane Transporter Activity
Peptide Antigen Binding
Biological Process
Carbohydrate Metabolic Process
Calcium Ion Transport
Amino Acid Transport
Phenylalanine Transport
Tryptophan Transport
Sodium Ion Transmembrane Transport
Response To Exogenous DsRNA
Leukocyte Migration
Leucine Import Across Plasma Membrane
L-alpha-amino Acid Transmembrane Transport
L-leucine Import Across Plasma Membrane
L-alanine Import Across Plasma Membrane
Amino Acid Transmembrane Transport
Amino Acid Transport
Response To Toxic Substance
Organic Cation Transport
Neutral Amino Acid Transport
Glycine Transport
Leucine Transport
Tryptophan Transport
Valine Transport
Proline Transmembrane Transport
Leukocyte Migration
Metal Ion Homeostasis
Thyroid Hormone Transport
Amino Acid Import Across Plasma Membrane
Leucine Import Across Plasma Membrane
Transport Across Blood-brain Barrier
Toxin Transport
L-leucine Import Across Plasma Membrane
L-alanine Import Across Plasma Membrane
Pathways
Basigin interactions
Amino acid transport across the plasma membrane
Defective SLC7A7 causes lysinuric protein intolerance (LPI)
Tryptophan catabolism
Basigin interactions
Amino acid transport across the plasma membrane
Drugs
Phenylalanine
Alanine
Diseases
GWAS
Iron status biomarkers (transferrin saturation) (
28334935
)
Interacting Genes
16 interacting genes:
CCR4
EBP
EGFR
GPR37
HNRNPD
ICAM1
ITGB1
MTNR1B
NPSR1
SLC7A10
SLC7A11
SLC7A5
SLC7A7
SLC7A8
TLCD3A
VHL
26 interacting genes:
ABHD16A
AGPAT4
AQP6
COMT
DERL1
FXYD6-FXYD2
MFF
MFSD3
NDUFA3
NINJ2
REEP4
SIGLEC5
SLC25A46
SLC30A2
SLC3A1
SLC3A2
SMPD2
SNORC
SYCE1L
SYNJ2BP
TMEM14B
TMEM208
TMEM60
TMEM65
YIPF1
YIPF6
Entrez ID
6520
23428
HPRD ID
01148
11971
Ensembl ID
ENSG00000168003
ENSG00000092068
Uniprot IDs
J3KPF3
P08195
Q53EM9
Q9UHI5
PDB IDs
2DH2
2DH3
6IRS
6IRT
6JMQ
6JMR
6S8V
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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