SLC3A2 and SLC7A7

Data Source:
HPRD (in vitro)

		SLC3A2	SLC7A7
Description		solute carrier family 3 member 2	solute carrier family 7 member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cell Junction Melanosome Extracellular Exosome Amino Acid Transport Complex	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	RNA Binding Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Cadherin Binding	Basic Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity
	Biological Process	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Phenylalanine Transport Tryptophan Transport Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Leucine Import Across Plasma Membrane L-alpha-amino Acid Transmembrane Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Regulation Of Arginine Metabolic Process Amino Acid Transmembrane Transport Amino Acid Transport L-amino Acid Transport Leukocyte Migration L-alpha-amino Acid Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways		Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism	Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI)
Drugs			Fluciclovine (18F)
Diseases			Lysinuric protein intolerance (LPI)
GWAS		Iron status biomarkers (transferrin saturation) ( 28334935)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Intraocular pressure ( 30591961) Iris color (b* coordinate) ( 30895295) Psychological resilience (outcome-based) in high deployment stress exposure ( 31081985) Resting-state electroencephalogram vigilance ( 29703947) Type 2 diabetes ( 30297969)
Interacting Genes		16 interacting genes: CCR4 EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL	2 interacting genes: NEDD4L SLC3A2
Entrez ID		6520	9056
HPRD ID		01148	04667
Ensembl ID		ENSG00000168003	ENSG00000155465
Uniprot IDs		J3KPF3 P08195	A0A0S2Z502 Q9UM01
PDB IDs		2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V
Enriched GO Terms of Interacting Partners?
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