RASAL3 and CCDC136

Data Source:
BioGRID (two hybrid)

		RASAL3	CCDC136
Description		RAS protein activator like 3	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	MAPK Cascade Positive Regulation Of GTPase Activity Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways		Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		23 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1	136 interacting genes: ABT1 AQP1 ASB7 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 C21orf58 CARD9 CBX8 CCDC120 CCDC13 CCDC146 CCDC185 CCDC187 CCDC6 CCHCR1 CDC5L CDK2AP1 CEP57 CEP57L1 CEP95 COIL CWF19L2 DDX6 DISC1 DTNB DYNC1I2 ENKD1 FAM107A FAM161A FAM161B FAM50B FLYWCH1 GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B HOXB5 ISCU JAKMIP2 JMY JRK KANSL1 KAT5 KIF5B KIFC3 LCA5L LENG1 MAGEB4 MBD3L2 MCRS1 MOS NDC80 NDN NEBL NEK6 NME7 NOP53 ODAD3 PDLIM5 PIBF1 PKN1 PKN2 POGZ PPP1R18 PRPF18 PRPF3 PRPF31 PRR35 PSMA1 PSMC5 PSMD9 RAB33A RAB33B RALBP1 RASAL3 RASSF8 SCNM1 SDHAF1 SHFL SMARCE1 SYT6 TBRG1 TCEA2 THAP7 TNNT1 TRAF3IP3 TSGA10 TSGA10IP TSPYL1 TXLNA UBQLN4 UBTFL1 USP2 WT1 ZBTB24 ZBTB38 ZBTB47 ZC2HC1C ZFP1 ZFYVE26 ZNF124 ZNF20 ZNF223 ZNF230 ZNF250 ZNF264 ZNF329 ZNF35 ZNF408 ZNF417 ZNF440 ZNF490 ZNF497 ZNF564 ZNF572 ZNF580 ZNF581 ZNF587 ZNF599 ZNF648 ZNF669 ZNF670 ZNF688 ZNF696 ZNF774 ZNF777 ZNF785 ZNF835 ZNF837 ZSCAN26
Entrez ID		64926	64753
HPRD ID		10977	10887
Ensembl ID		ENSG00000105122	ENSG00000128596
Uniprot IDs		Q86YV0	A0A024R758 Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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