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CCDC136 and DYNC1I2
Data Source:
BioGRID
(two hybrid)
CCDC136
DYNC1I2
Description
coiled-coil domain containing 136
dynein cytoplasmic 1 intermediate chain 2
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Membrane
Integral Component Of Membrane
Cytoplasm
Centrosome
Cytosol
Cytoplasmic Dynein Complex
Microtubule
Vesicle
Molecular Function
Microtubule Motor Activity
Protein Binding
Dynein Light Chain Binding
Dynein Heavy Chain Binding
Biological Process
Acrosome Assembly
Spermatogenesis
Single Fertilization
G2/M Transition Of Mitotic Cell Cycle
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Movement
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Transport Along Microtubule
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Ciliary Basal Body-plasma Membrane Docking
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Reading disability or specific language impairment (pleiotropy) (
25065397
)
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) (
25065397
)
Hippocampal volume (
25625606
)
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Weight (
28552196
)
Interacting Genes
136 interacting genes:
ABT1
AQP1
ASB7
ATP5PO
ATXN1
BARD1
BLOC1S6
BYSL
C1orf216
C21orf58
CARD9
CBX8
CCDC120
CCDC13
CCDC146
CCDC185
CCDC187
CCDC6
CCHCR1
CDC5L
CDK2AP1
CEP57
CEP57L1
CEP95
COIL
CWF19L2
DDX6
DISC1
DTNB
DYNC1I2
ENKD1
FAM107A
FAM161A
FAM161B
FAM50B
FLYWCH1
GFI1B
HAUS1
HDAC4
HGS
HMG20A
HMG20B
HOXB5
ISCU
JAKMIP2
JMY
JRK
KANSL1
KAT5
KIF5B
KIFC3
LCA5L
LENG1
MAGEB4
MBD3L2
MCRS1
MOS
NDC80
NDN
NEBL
NEK6
NME7
NOP53
ODAD3
PDLIM5
PIBF1
PKN1
PKN2
POGZ
PPP1R18
PRPF18
PRPF3
PRPF31
PRR35
PSMA1
PSMC5
PSMD9
RAB33A
RAB33B
RALBP1
RASAL3
RASSF8
SCNM1
SDHAF1
SHFL
SMARCE1
SYT6
TBRG1
TCEA2
THAP7
TNNT1
TRAF3IP3
TSGA10
TSGA10IP
TSPYL1
TXLNA
UBQLN4
UBTFL1
USP2
WT1
ZBTB24
ZBTB38
ZBTB47
ZC2HC1C
ZFP1
ZFYVE26
ZNF124
ZNF20
ZNF223
ZNF230
ZNF250
ZNF264
ZNF329
ZNF35
ZNF408
ZNF417
ZNF440
ZNF490
ZNF497
ZNF564
ZNF572
ZNF580
ZNF581
ZNF587
ZNF599
ZNF648
ZNF669
ZNF670
ZNF688
ZNF696
ZNF774
ZNF777
ZNF785
ZNF835
ZNF837
ZSCAN26
8 interacting genes:
CCDC136
DCTN1
DYNLRB1
DYNLT1
DYNLT3
NECAB2
PNN
PPFIA1
Entrez ID
64753
1781
HPRD ID
10887
04512
Ensembl ID
ENSG00000128596
ENSG00000077380
Uniprot IDs
A0A024R758
Q96JN2
A0A140VKE9
B4DPZ3
Q13409
PDB IDs
5JPW
6F1T
6F1U
6F1Z
6F38
6F3A
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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