AIDA and DDX41

Data Source:
BioGRID (two hybrid)

		AIDA	DDX41
Description		axin interactor, dorsalization associated	DEAD-box helicase 41
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Membrane	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Dorsal/ventral Pattern Formation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Determination Of Ventral Identity	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation Positive Regulation Of Type I Interferon Production
Pathways			STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: APP DDIT4L DDX41 EMSY FAM118A LNX1 PINX1 PLEKHF2 RPL36A ZDHHC17	7 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL SIAH1 TUBG1
Entrez ID		64853	51428
HPRD ID		07798	10490
Ensembl ID		ENSG00000186063	ENSG00000183258
Uniprot IDs		Q96BJ3	B3KRK2 Q9UJV9
PDB IDs			2P6N 5GVR 5GVS 5H1Y
Enriched GO Terms of Interacting Partners?
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