GINS3 and TRAPPC6A

Data Source:
BioGRID (two hybrid)

		GINS3	TRAPPC6A
Description		GINS complex subunit 3	trafficking protein particle complex subunit 6A
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GO Annotations	Cellular Component	GINS Complex Nucleoplasm CMG Complex	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		Unwinding of DNA Unwinding of DNA	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) QT interval ( 19305408) TPE interval (resting) ( 32386560)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		8 interacting genes: CTNNA3 GINS4 KRT80 MEOX2 MYO15B SMARCD1 TRAPPC6A VAC14	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		64785	79090
HPRD ID		07842	14503
Ensembl ID		ENSG00000181938	ENSG00000007255
Uniprot IDs		A0A0S2Z5L0 A0A0S2Z5L4 A0A0S2Z5P2 Q9BRX5	B7TZ90 O75865
PDB IDs		2E9X 2EHO 2Q9Q 6XTX 6XTY	2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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