SMYD3 and NDUFAB1

Data Source:
BioGRID (two hybrid)

		SMYD3	NDUFAB1
Description		SET and MYND domain containing 3	NADH:ubiquinone oxidoreductase subunit AB1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Mitochondrial Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Complex Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Acyl Binding Acyl Carrier Activity Fatty Acid Binding Calcium Ion Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dexamethasone Stimulus	Mitochondrial Electron Transport, NADH To Ubiquinone Fatty Acid Biosynthetic Process Protein Lipoylation Mitochondrial Respiratory Chain Complex I Assembly
Pathways		PKMTs methylate histone lysines	Glyoxylate metabolism and glycine degradation Respiratory electron transport Complex I biogenesis Mitochondrial Fatty Acid Beta-Oxidation
Drugs			NADH
Diseases
GWAS		Bipolar disorder ( 31043756) Blood metabolite levels ( 26401656) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fractional exhaled nitric oxide (childhood) ( 24315451) Gut microbiota relative abundance (Bifidobacterium) ( 33208821) Malaria ( 31844061) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) PR interval ( 32439900) Renal underexcretion gout ( 32238385) Response to serotonin reuptake inhibitors in non-psychotic unipolar depression ( 26348319) Systemic lupus erythematosus ( 29848360) Upper eyelid sagging severity ( 24869959)	Bipolar disorder ( 17554300)
Interacting Genes		21 interacting genes: APP CAMK2B CSTF2T CYP39A1 EED EZH2 H3-4 H3-5 HELZ HSP90AA1 MKRN3 NDUFAB1 NFYB NUP54 PBX2 PKN1 POLR2K SHC3 TRIT1 VANGL1 ZNF557	35 interacting genes: ACTN3 BBC3 BEX5 CCDC24 CNTF EIF3B ERBB3 FEM1A FHL3 FNDC3B HINFP KCTD9 LMO2 LNX1 MBLAC1 MORN3 MRPL23 NOXA1 NRF1 NT5C3A NTAQ1 OIP5 POP5 PPP1R16A PSMC3 RBM18 SLIRP SMYD3 THAP1 TLX3 TOX2 VAC14 ZNF19 ZNF410 ZNF829
Entrez ID		64754	4706
HPRD ID		12297	11951
Ensembl ID		ENSG00000185420	ENSG00000004779
Uniprot IDs		B3KN46 Q9H7B4	O14561
PDB IDs		3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0 5CCL 5CCM 5EX0 5EX3 5HI7 5HQ8 5V37 5XXD 5XXG 5XXJ 5YJO 6IJL 6O9O 6P6G 6P6K 6P7Z 6PAF	2DNW 5OOL 5OOM 5XTB 5XTC 5XTD 5XTH 5XTI 6ODD
Enriched GO Terms of Interacting Partners?
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