NDUFAB1 and CNTF

Data Source:
BioGRID (two hybrid)

		NDUFAB1	CNTF
Description		NADH:ubiquinone oxidoreductase subunit AB1	ciliary neurotrophic factor
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Mitochondrial Membrane	Extracellular Region Extracellular Space Cytoplasm Axon
	Molecular Function	Acyl Binding Acyl Carrier Activity Fatty Acid Binding Calcium Ion Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Protein Binding Growth Factor Activity Protein-containing Complex Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Fatty Acid Biosynthetic Process Protein Lipoylation Mitochondrial Respiratory Chain Complex I Assembly	Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Astrocyte Activation Muscle Organ Morphogenesis Neuron Development Positive Regulation Of Axon Regeneration Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways		Glyoxylate metabolism and glycine degradation Respiratory electron transport Complex I biogenesis Mitochondrial Fatty Acid Beta-Oxidation	IL-6-type cytokine receptor ligand interactions
Drugs		NADH
Diseases
GWAS		Bipolar disorder ( 17554300)	Diastolic blood pressure ( 27841878) Inflammatory bowel disease ( 23128233) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)
Interacting Genes		35 interacting genes: ACTN3 BBC3 BEX5 CCDC24 CNTF EIF3B ERBB3 FEM1A FHL3 FNDC3B HINFP KCTD9 LMO2 LNX1 MBLAC1 MORN3 MRPL23 NOXA1 NRF1 NT5C3A NTAQ1 OIP5 POP5 PPP1R16A PSMC3 RBM18 SLIRP SMYD3 THAP1 TLX3 TOX2 VAC14 ZNF19 ZNF410 ZNF829	13 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 TEPSIN TRIP6
Entrez ID		4706	1270
HPRD ID		11951	00347
Ensembl ID		ENSG00000004779	ENSG00000242689
Uniprot IDs		O14561	P26441
PDB IDs		2DNW 5OOL 5OOM 5XTB 5XTC 5XTD 5XTH 5XTI 6ODD	1CNT
Enriched GO Terms of Interacting Partners?
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