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ITSN1 and MTUS2
Data Source:
BioGRID
(two hybrid)
ITSN1
MTUS2
Description
intersectin 1
microtubule associated scaffold protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Cytoplasm
Cytosol
Plasma Membrane
Clathrin-coated Pit
Lamellipodium
Presynaptic Membrane
Neuronal Cell Body
Dendritic Spine
Recycling Endosome
Apical Dendrite
Intracellular Vesicle
Presynapse
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
Nucleus
Cytoplasm
Centrosome
Cytoplasmic Microtubule
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Molecular Adaptor Activity
Proline-rich Region Binding
Protein Binding
Microtubule Binding
Protein Homodimerization Activity
Biological Process
Exocytosis
Endocytosis
G Protein-coupled Receptor Signaling Pathway
Brain Development
Protein Transport
Viral Process
Endosomal Transport
Cellular Protein Localization
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Ephrin Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Growth Hormone Secretion
Positive Regulation Of Dendritic Spine Development
Membrane Organization
Clathrin-dependent Synaptic Vesicle Endocytosis
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Caveolin-mediated Endocytosis
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
EPHB-mediated forward signaling
EPHB-mediated forward signaling
G alpha (12/13) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Bitter non-alcoholic beverage consumption (
31046077
)
Educational attainment (
25201988
)
Height (
31562340
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
QT interval (
29213071
)
Red blood cell count (
32888494
)
Red cell distribution width (
32888494
27863252
)
Tonsillectomy (
27182965
28928442
)
Insomnia (caffeine-induced) (
22754043
)
Obesity-related traits (
23251661
)
Triptolide cytotoxicity (
26121980
)
Interacting Genes
87 interacting genes:
AGFG1
AGFG2
AP2B1
ARF6
ARFIP2
ARHGAP31
ASAP2
CCNO
CDC42
CEP85L
CLIP2
CLTC
CSNK2B
CYTH1
DAB1
DAB2
DES
DISC1
DLGAP1
DNM1
DNM2
EEF1A1
EPHB2
EPN2
EPS15
EPS15L1
FCHO1
FCHO2
FCHSD2
FNBP1
FNBP4
GAREM2
GCC1
GOLGA5
HIP1
HRAS
ITSN2
KHDRBS1
KIF16B
KIF5A
LMO4
MAP3K20
MAPK6
MAPK8IP2
MRPL20
MTUS2
PACSIN3
PDCD6IP
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
RAB11FIP2
RAB5A
RABEP1
RAI14
RNF40
RPS6KA5
SCAMP1
SCOC
SF3B4
SGIP1
SH3GL2
SMARCC2
SNAP23
SNAP25
SNX5
SOS1
SPDL1
SPRY2
STON2
SYNJ1
SYNJ2
TK1
TRIM8
TSG101
UBE2K
UNC119
VLDLR
WASL
WBP11
ZFPM2
326 interacting genes:
-
ABHD15
ACSM1
AEN
AFF4
AKT1
ANKRD11
ANKS1A
AQP1
ARL4A
ARNT2
AXIN1
BANF2
BARD1
BCL6
BEX2
BMP7
BYSL
C19orf44
C1orf109
C1orf216
C1orf35
C21orf58
C2CD6
C8orf34
CACNB3
CATIP
CATSPER1
CBX8
CCAR1
CCDC116
CCDC120
CCDC146
CCDC17
CCDC185
CCDC187
CCDC198
CCDC6
CCDC60
CCHCR1
CDC20B
CDC5L
CDC7
CDC73
CDK18
CDK5R1
CDKL3
CDKN1A
CDKN1B
CEP57L1
CEP95
CERK
CHIC2
CNNM3
COG2
CREB5
CRY2
CSF1
CTSZ
CWF19L2
CXCL11
CXCL16
CYSLTR2
DCDC2B
DCTN4
DCX
DDX6
DHRS1
DLGAP4
DLGAP5
DMRT3
DOCK2
DTNB
EHHADH
EIF3D
ENKD1
ENPP7
EXOC8
FAM107A
FAM110A
FAM124B
FAM13C
FAM161A
FAM161B
FAM71E2
FAM74A4
FAM90A1
FASTKD5
FBXL18
FBXO34
FBXW5
FCHSD2
FHL3
FLYWCH1
FNDC11
GADD45GIP1
GAL3ST2
GAS2L2
GEM
GGN
GNL3L
GOLGA2P11
GPKOW
GRAP2
GSTP1
GTF2I
GTPBP10
HAPLN2
HAUS1
HBZ
HCK
HDAC4
HOXB5
HOXB9
HSF2
ICAM4
IL16
INO80B
IQCE
ITGB4
ITGB5
ITSN1
JMY
JOSD1
JRK
KANK2
KAT5
KIF1A
KIFC3
KRT6A
KRT75
KRT76
LENG1
LIMS2
LINC00636
LMO2
LMO3
LMO4
LNX1
LRR1
LYSMD1
MAGEA8
MARK4
MBD3
METTL17
MFAP1
MOS
MRPL11
MTMR6
MYO15B
MYOM1
MYPOP
NDEL1
NDOR1
NEFL
NELFE
NHSL2
NTAQ1
NUBPL
NUDT10
NXF1
ODAD3
ODF1
PCDHB14
PDE4DIP
PDZD4
PIBF1
PIN1
PKN1
PKN3
PKP2
PLEKHN1
PLK4
PLSCR4
POLDIP2
POLDIP3
PPHLN1
PPP1R18
PRKAA1
PRKAA2
PRPF18
PRPF31
PRR35
PSMA1
PSMB1
PTCD1
PTK7
PTPMT1
RAB3IL1
RALY
RANBP3L
RAP1B
RASAL3
RASD1
RBM41
RCOR3
RGS2
RHPN1
RIBC2
RNF6
ROBO3
RPA1
RPL9
RPS19BP1
RTP5
SAMD4A
SCEL
SCNM1
SDCBP
SELENOM
SETD5
SH2D4A
SH3RF2
SHFL
SLC22A5
SLC23A1
SLC25A42
SLC25A48
SLC25A6
SLIRP
SMARCD1
SMARCE1
SMG9
SNAI1
SNHG11
SNRPA
SNRPB2
SNW1
SPATA8
SPATC1L
SPG21
SPG7
STK16
SYT6
TACO1
TAF13
TBC1D22B
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP7
TLE5
TNIP3
TNNI1
TP53RK
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC23
TTLL10
TULP2
TXN2
UBTFL1
USP2
USP22
UTP14C
VASN
WAC
ZBTB16
ZBTB38
ZBTB47
ZC2HC1C
ZFC3H1
ZFHX3
ZFP1
ZFP2
ZFP64
ZFYVE21
ZMAT2
ZMYND10
ZNF124
ZNF136
ZNF17
ZNF20
ZNF224
ZNF23
ZNF230
ZNF232
ZNF239
ZNF250
ZNF266
ZNF3
ZNF329
ZNF337
ZNF35
ZNF408
ZNF410
ZNF414
ZNF415
ZNF417
ZNF426
ZNF438
ZNF439
ZNF440
ZNF48
ZNF490
ZNF497
ZNF512B
ZNF557
ZNF564
ZNF572
ZNF580
ZNF581
ZNF587
ZNF599
ZNF607
ZNF613
ZNF624
ZNF648
ZNF655
ZNF669
ZNF670
ZNF696
ZNF76
ZNF764
ZNF774
ZNF775
ZNF785
ZNF792
ZNF837
ZNF844
ZSCAN12
ZSCAN26
Entrez ID
6453
23281
HPRD ID
03898
11108
Ensembl ID
ENSG00000205726
ENSG00000132938
Uniprot IDs
A7XZY7
F8W7U0
Q15811
Q6PD56
Q5JR59
PDB IDs
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
5HZI
5HZJ
5HZK
6GBU
6H5T
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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