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MTUS2 and RPA1
Data Source:
BioGRID
(two hybrid, two hybrid)
MTUS2
RPA1
Description
microtubule associated scaffold protein 2
replication protein A1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytoplasmic Microtubule
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
PML Body
Site Of DNA Damage
Molecular Function
Protein Binding
Microtubule Binding
Protein Homodimerization Activity
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Single-stranded Telomeric DNA Binding
Metal Ion Binding
G-rich Strand Telomeric DNA Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Replication
DNA-dependent DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
DNA Recombination
Cellular Response To DNA Damage Stimulus
Telomere Maintenance Via Telomerase
Translesion Synthesis
Telomere Maintenance Via Semi-conservative Replication
Nucleotide-excision Repair, DNA Incision
Protein Localization To Chromosome
Interstrand Cross-link Repair
Error-prone Translesion Synthesis
DNA Damage Response, Detection Of DNA Damage
Meiotic Cell Cycle
Error-free Translesion Synthesis
Regulation Of Cellular Response To Heat
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Removal of the Flap Intermediate from the C-strand
Activation of ATR in response to replication stress
SUMOylation of DNA damage response and repair proteins
Regulation of HSF1-mediated heat shock response
HSF1 activation
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
Activation of the pre-replicative complex
Removal of the Flap Intermediate
G2/M DNA damage checkpoint
Meiotic recombination
Drugs
Diseases
GWAS
Insomnia (caffeine-induced) (
22754043
)
Obesity-related traits (
23251661
)
Triptolide cytotoxicity (
26121980
)
Airway imaging phenotypes (
26030696
)
Bipolar disorder (
31043756
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Interacting Genes
326 interacting genes:
-
ABHD15
ACSM1
AEN
AFF4
AKT1
ANKRD11
ANKS1A
AQP1
ARL4A
ARNT2
AXIN1
BANF2
BARD1
BCL6
BEX2
BMP7
BYSL
C19orf44
C1orf109
C1orf216
C1orf35
C21orf58
C2CD6
C8orf34
CACNB3
CATIP
CATSPER1
CBX8
CCAR1
CCDC116
CCDC120
CCDC146
CCDC17
CCDC185
CCDC187
CCDC198
CCDC6
CCDC60
CCHCR1
CDC20B
CDC5L
CDC7
CDC73
CDK18
CDK5R1
CDKL3
CDKN1A
CDKN1B
CEP57L1
CEP95
CERK
CHIC2
CNNM3
COG2
CREB5
CRY2
CSF1
CTSZ
CWF19L2
CXCL11
CXCL16
CYSLTR2
DCDC2B
DCTN4
DCX
DDX6
DHRS1
DLGAP4
DLGAP5
DMRT3
DOCK2
DTNB
EHHADH
EIF3D
ENKD1
ENPP7
EXOC8
FAM107A
FAM110A
FAM124B
FAM13C
FAM161A
FAM161B
FAM71E2
FAM74A4
FAM90A1
FASTKD5
FBXL18
FBXO34
FBXW5
FCHSD2
FHL3
FLYWCH1
FNDC11
GADD45GIP1
GAL3ST2
GAS2L2
GEM
GGN
GNL3L
GOLGA2P11
GPKOW
GRAP2
GSTP1
GTF2I
GTPBP10
HAPLN2
HAUS1
HBZ
HCK
HDAC4
HOXB5
HOXB9
HSF2
ICAM4
IL16
INO80B
IQCE
ITGB4
ITGB5
ITSN1
JMY
JOSD1
JRK
KANK2
KAT5
KIF1A
KIFC3
KRT6A
KRT75
KRT76
LENG1
LIMS2
LINC00636
LMO2
LMO3
LMO4
LNX1
LRR1
LYSMD1
MAGEA8
MARK4
MBD3
METTL17
MFAP1
MOS
MRPL11
MTMR6
MYO15B
MYOM1
MYPOP
NDEL1
NDOR1
NEFL
NELFE
NHSL2
NTAQ1
NUBPL
NUDT10
NXF1
ODAD3
ODF1
PCDHB14
PDE4DIP
PDZD4
PIBF1
PIN1
PKN1
PKN3
PKP2
PLEKHN1
PLK4
PLSCR4
POLDIP2
POLDIP3
PPHLN1
PPP1R18
PRKAA1
PRKAA2
PRPF18
PRPF31
PRR35
PSMA1
PSMB1
PTCD1
PTK7
PTPMT1
RAB3IL1
RALY
RANBP3L
RAP1B
RASAL3
RASD1
RBM41
RCOR3
RGS2
RHPN1
RIBC2
RNF6
ROBO3
RPA1
RPL9
RPS19BP1
RTP5
SAMD4A
SCEL
SCNM1
SDCBP
SELENOM
SETD5
SH2D4A
SH3RF2
SHFL
SLC22A5
SLC23A1
SLC25A42
SLC25A48
SLC25A6
SLIRP
SMARCD1
SMARCE1
SMG9
SNAI1
SNHG11
SNRPA
SNRPB2
SNW1
SPATA8
SPATC1L
SPG21
SPG7
STK16
SYT6
TACO1
TAF13
TBC1D22B
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP7
TLE5
TNIP3
TNNI1
TP53RK
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC23
TTLL10
TULP2
TXN2
UBTFL1
USP2
USP22
UTP14C
VASN
WAC
ZBTB16
ZBTB38
ZBTB47
ZC2HC1C
ZFC3H1
ZFHX3
ZFP1
ZFP2
ZFP64
ZFYVE21
ZMAT2
ZMYND10
ZNF124
ZNF136
ZNF17
ZNF20
ZNF224
ZNF23
ZNF230
ZNF232
ZNF239
ZNF250
ZNF266
ZNF3
ZNF329
ZNF337
ZNF35
ZNF408
ZNF410
ZNF414
ZNF415
ZNF417
ZNF426
ZNF438
ZNF439
ZNF440
ZNF48
ZNF490
ZNF497
ZNF512B
ZNF557
ZNF564
ZNF572
ZNF580
ZNF581
ZNF587
ZNF599
ZNF607
ZNF613
ZNF624
ZNF648
ZNF655
ZNF669
ZNF670
ZNF696
ZNF76
ZNF764
ZNF774
ZNF775
ZNF785
ZNF792
ZNF837
ZNF844
ZSCAN12
ZSCAN26
68 interacting genes:
AICDA
AKTIP
ANXA1
ANXA7
ASCC2
ATM
BID
BLM
BRCA2
BRIP1
CCNA1
CCNA2
CCNB1
CDC5L
CPE
CSNK2B
DMC1
EHMT2
ERCC1
ERCC4
EXO5
GNB5
HAX1
HELB
HGH1
HNRNPUL1
HSPA6
HUS1
MCM2
MCM4
MCM6
MCM7
MMS22L
MSH4
MTUS2
MUTYH
ORC2
ORC6
PAXIP1
PCNA
POLL
PRIMPOL
PRKDC
RAD1
RAD23B
RAD51
RAD52
RAD9A
RBM23
RCC1
RECQL
RFWD3
RPA2
RPA3
RPA4
RPS6KA5
SELENBP1
SEM1
SMAD3
TCEA2
TK1
TP53
TREX1
VIM
WRN
XPA
XPC
ZBTB14
Entrez ID
23281
6117
HPRD ID
11108
01565
Ensembl ID
ENSG00000132938
ENSG00000132383
Uniprot IDs
Q5JR59
P27694
PDB IDs
1EWI
1FGU
1JMC
1L1O
2B29
2B3G
4IJH
4IJL
4IPC
4IPD
4IPG
4IPH
4LUO
4LUV
4LUZ
4LW1
4LWC
4NB3
4O0A
4R4C
4R4I
4R4O
4R4Q
4R4T
5E7N
5EAY
5N85
5N8A
Enriched GO Terms of Interacting Partners
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