INF2 and UBE2R2

Data Source:
BioGRID (two hybrid)

		INF2	UBE2R2
Description		inverted formin 2	ubiquitin conjugating enzyme E2 R2
Image		No pdb structure
GO Annotations	Cellular Component	Perinuclear Region Of Cytoplasm	Cytosol
	Molecular Function	Actin Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Actin Cytoskeleton Organization Regulation Of Mitochondrial Fission	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS			Bipolar disorder ( 20351715) Body mass index ( 25673413) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: BDKRB2 CSNK2A1 SPOP UBE2R2	27 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 GSC2 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 SDCBP UBA1 UBC
Entrez ID		64423	54926
HPRD ID		08648	15602
Ensembl ID		ENSG00000203485	ENSG00000107341
Uniprot IDs		Q27J81	Q712K3
PDB IDs			6NYO
Enriched GO Terms of Interacting Partners?
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