UBE2R2 and RNF113B

Data Source:
BioGRID (two hybrid)

		UBE2R2	RNF113B
Description		ubiquitin conjugating enzyme E2 R2	ring finger protein 113B
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GO Annotations	Cellular Component	Cytosol	U2-type Spliceosomal Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Metal Ion Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination	SnoRNA Splicing
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Body mass index ( 25673413) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278)	Clozapine-induced agranulocytosis ( 25187353) Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 GSC2 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 SDCBP UBA1 UBC	4 interacting genes: UBE2H UBE2L3 UBE2R2 UBE2U
Entrez ID		54926	140432
HPRD ID		15602	15745
Ensembl ID		ENSG00000107341	ENSG00000139797
Uniprot IDs		Q712K3	Q8IZP6
PDB IDs		6NYO	2CSY
Enriched GO Terms of Interacting Partners?
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