UBE2R2 and INF2

Data Source:
BioGRID (two hybrid)

		UBE2R2	INF2
Description		ubiquitin conjugating enzyme E2 R2	inverted formin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Actin Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination	Actin Cytoskeleton Organization Regulation Of Mitochondrial Fission
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS		Bipolar disorder ( 20351715) Body mass index ( 25673413) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 GSC2 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 SDCBP UBA1 UBC	4 interacting genes: BDKRB2 CSNK2A1 SPOP UBE2R2
Entrez ID		54926	64423
HPRD ID		15602	08648
Ensembl ID		ENSG00000107341	ENSG00000203485
Uniprot IDs		Q712K3	Q27J81
PDB IDs		6NYO
Enriched GO Terms of Interacting Partners?
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