TMPPE and SLC38A1

Data Source:
BioGRID (two hybrid)

		TMPPE	SLC38A1
Description		transmembrane protein with metallophosphoesterase domain	solute carrier family 38 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Amino Acid:sodium Symporter Activity Neutral Amino Acid:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity
	Biological Process		Neurotransmitter Uptake Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Neutral Amino Acid Transport L-amino Acid Transport Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport
Pathways			Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs			Asparagine
Diseases
GWAS		Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433)	Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1	30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1
Entrez ID		643853	81539
HPRD ID		18951	12245
Ensembl ID		ENSG00000188167	ENSG00000111371
Uniprot IDs		Q6ZT21	A0A024R124 F8VX04 Q9H2H9
PDB IDs
Enriched GO Terms of Interacting Partners?
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