TMPPE and CYB561

Data Source:
BioGRID (two hybrid)

		TMPPE	CYB561
Description		transmembrane protein with metallophosphoesterase domain	cytochrome b561
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Lysosomal Membrane Integral Component Of Membrane Transport Vesicle Membrane
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process		Electron Transport Chain
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)
Interacting Genes		35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1	59 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35C2 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7
Entrez ID		643853	1534
HPRD ID		18951	02485
Ensembl ID		ENSG00000188167	ENSG00000008283
Uniprot IDs		Q6ZT21	B3KTA1 J3QRH5 P49447
PDB IDs
Enriched GO Terms of Interacting Partners?
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