SLC38A1 and AMIGO1

Data Source:
BioGRID (two hybrid)

		SLC38A1	AMIGO1
Description		solute carrier family 38 member 1	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane	Voltage-gated Potassium Channel Complex Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket
	Molecular Function	Amino Acid:sodium Symporter Activity Neutral Amino Acid:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity	Protein Binding Potassium Channel Regulator Activity
	Biological Process	Neurotransmitter Uptake Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Neutral Amino Acid Transport L-amino Acid Transport Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs		Asparagine
Diseases
GWAS		Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549)
Interacting Genes		30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		81539	57463
HPRD ID		12245	11129
Ensembl ID		ENSG00000111371	ENSG00000181754
Uniprot IDs		A0A024R124 F8VX04 Q9H2H9	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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