TMPPE and CNR2

Data Source:
BioGRID (two hybrid)

		TMPPE	CNR2
Description		transmembrane protein with metallophosphoesterase domain	cannabinoid receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perikaryon
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding
	Biological Process		Response To Amphetamine Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Metabolic Process Sensory Perception Of Pain Leukocyte Chemotaxis Negative Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Cannabinoid Signaling Pathway Negative Regulation Of Action Potential Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity
Pathways			Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
Drugs			Dronabinol Nabilone Ricinoleic Acid Lasofoxifene Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols
Diseases
GWAS		Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244) Psychotic experience (distressing) ( 31553412)
Interacting Genes		35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1	24 interacting genes: ADAM21 ADIPOQ AGPAT4 CCL4 COMT FXYD3 GNA15 MUC15 NRM PEDS1-UBE2V1 RFT1 SELENOK SLC35E4 SLC39A2 TMEM19 TMEM203 TMEM242 TMEM60 TMEM86A TMPPE TSPO2 YIPF1 YIPF4 YIPF6
Entrez ID		643853	1269
HPRD ID		18951	05444
Ensembl ID		ENSG00000188167	ENSG00000188822
Uniprot IDs		Q6ZT21	A0A024RAH7 P34972
PDB IDs			2KI9 5ZTY 6KPC 6KPF 6PT0
Enriched GO Terms of Interacting Partners?
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