AZI2 and MIB1

Data Source:
BioGRID (pull down)

		AZI2	MIB1
Description		5-azacytidine induced 2	MIB E3 ubiquitin protein ligase 1
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GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling Viral Process T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323)	Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Severe progression in rheumatoid arthritis ( 29065906)
Interacting Genes		13 interacting genes: APBA3 FAM107A IKBKE MIB1 MTPAP N4BP1 RB1CC1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA	15 interacting genes: AZI2 BLM DAB2 DAPK1 EPB41L4A GABARAP JAG1 SNX5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W
Entrez ID		64343	57534
HPRD ID		10577	06660
Ensembl ID		ENSG00000163512	ENSG00000101752
Uniprot IDs		Q9H6S1	Q86YT6
PDB IDs		5EP6 5Z7G 5Z7L	4TSE 4XI6 4XI7 4XIB
Enriched GO Terms of Interacting Partners?
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