MIB1 and AZI2

Data Source:
BioGRID (pull down)

		MIB1	AZI2
Description		MIB E3 ubiquitin protein ligase 1	5-azacytidine induced 2
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling Viral Process T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Severe progression in rheumatoid arthritis ( 29065906)	Cognitive decline (age-related) ( 28078323)
Interacting Genes		15 interacting genes: AZI2 BLM DAB2 DAPK1 EPB41L4A GABARAP JAG1 SNX5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W	13 interacting genes: APBA3 FAM107A IKBKE MIB1 MTPAP N4BP1 RB1CC1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA
Entrez ID		57534	64343
HPRD ID		06660	10577
Ensembl ID		ENSG00000101752	ENSG00000163512
Uniprot IDs		Q86YT6	Q9H6S1
PDB IDs		4TSE 4XI6 4XI7 4XIB	5EP6 5Z7G 5Z7L
Enriched GO Terms of Interacting Partners?
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