MIB1 and EPB41L4A

Data Source:
BioGRID (two hybrid)

		MIB1	EPB41L4A
Description		MIB E3 ubiquitin protein ligase 1	erythrocyte membrane protein band 4.1 like 4A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle	Cellular_component Cytoplasm Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Molecular_function Cytoskeletal Protein Binding
	Biological Process	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis	Biological_process Actomyosin Structure Organization
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Severe progression in rheumatoid arthritis ( 29065906)	Common carotid intima-media thickness in HIV negative individuals ( 29206233) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Suicide ideation score in major depressive disorder ( 26079190) Thyroid cancer ( 28195142) vWF and FVIII levels ( 21810271)
Interacting Genes		15 interacting genes: AZI2 BLM DAB2 DAPK1 EPB41L4A GABARAP JAG1 SNX5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W	5 interacting genes: APP MIB1 SRPK1 SRPK2 TNS2
Entrez ID		57534	64097
HPRD ID		06660	09939
Ensembl ID		ENSG00000101752	ENSG00000129595
Uniprot IDs		Q86YT6	Q8N8X1 Q8NEH8 Q9HCS5
PDB IDs		4TSE 4XI6 4XI7 4XIB
Enriched GO Terms of Interacting Partners?
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