RAB4A and FAM71C

Data Source:
BioGRID (two hybrid)

		RAB4A	FAM71C
Description		RAB4A, member RAS oncogene family	family with sequence similarity 71 member C
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS		Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	20 interacting genes: BANP CYSRT1 DNAJB9 FHL3 FHL5 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-8 KRTAP3-2 NBPF19 NOTCH2NLA P4HB PDLIM7 RAB14 RAB2A RAB2B RAB4A RAB4B
Entrez ID		5867	196472
HPRD ID		01541	17539
Ensembl ID		ENSG00000168118	ENSG00000180219
Uniprot IDs		A0A024R3U9 A0A087WYT5 P20338	Q8NEG0
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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