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DMRTB1 and CTBP1
Data Source:
BioGRID
(two hybrid)
DMRTB1
CTBP1
Description
DMRT like family B with proline rich C-terminal 1
C-terminal binding protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
RNA Polymerase II Transcription Corepressor Binding
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Domain Specific Binding
Identical Protein Binding
NAD Binding
Repressing Transcription Factor Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Germ Cell Development
Sex Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Protein Phosphorylation
Negative Regulation Of Cell Population Proliferation
Viral Genome Replication
Positive Regulation Of Histone Deacetylation
Negative Regulation Of Histone Acetylation
Negative Regulation Of Transcription, DNA-templated
White Fat Cell Differentiation
Regulation Of Cell Cycle
Negative Regulation Of Histone H4 Acetylation
Pathways
Deactivation of the beta-catenin transactivating complex
SUMOylation of transcription cofactors
Repression of WNT target genes
Signaling by TCF7L2 mutants
Drugs
Formic acid
Diseases
GWAS
Cerebrospinal fluid AB1-42 levels (
28247064
)
Response to statin therapy (
20339536
)
Type 2 diabetes (
31118516
32499647
)
Interacting Genes
40 interacting genes:
C1orf94
CCND3
CDKN2D
CTBP1
CTBP2
EWSR1
EXOSC1
EXOSC5
EYA2
FXR2
HNRNPUL1
IL16
INCA1
KRTAP19-5
KRTAP19-6
KRTAP21-2
KRTAP8-1
LENG8
NCKIPSD
NEDD9
NIF3L1
PARD6G
PEF1
PKP2
PRMT2
QKI
RAMAC
RBFOX1
RBFOX2
RBM14
RBPMS
RPA2
SH3RF1
SLAIN1
SORBS3
TENT5A
TLE5
TOX
TSG101
VASP
92 interacting genes:
ACTL6B
AKAP9
APC
ARNT2
ATXN1L
BCAS3
BCL3
BMPR2
BRCA1
CBX4
CDC23
CDKN2D
CEP68
CHD3
CREBBP
CRY2
CTBP2
CTNNA1
DGCR6
DMRTB1
EEF1D
ELAC2
ELK3
EP300
FANCC
FANCF
FANCG
FANCL
FOXP1
FOXP2
FUNDC1
GTF2B
H3-4
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC9
HEMGN
HIC1
HOXB5
HTT
IKZF1
IKZF2
KAT2B
KDM1A
KLF12
KLF3
LCORL
LNX1
MAML2
MAPK9
MARCHF10
MECOM
NME2
NOL4
NOL4L
NOS1
NRIP1
NTAQ1
ORC4
PIAS2
PLCB1
PNN
PRKAA1
PRKCI
RAI2
RB1
RBBP5
RBBP8
RBM14
RCOR1
RNF111
SIN3A
SNRPN
SOBP
SPEN
TBP
TCF4
TEAD4
TERF2
TERF2IP
TGIF1
THAP11
TSHZ3
ZBP1
ZBTB18
ZEB1
ZEB2
ZFPM2
ZNF219
Entrez ID
63948
1487
HPRD ID
16828
04015
Ensembl ID
ENSG00000143006
ENSG00000159692
Uniprot IDs
I6L9A0
Q96MA1
Q13363
X5D8Y5
PDB IDs
1MX3
4LCE
4U6Q
4U6S
6CDF
6CDR
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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