GPSM3 and IVD

Data Source:
BioGRID (two hybrid)

		GPSM3	IVD
Description		G protein signaling modulator 3	isovaleryl-CoA dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Mitochondrial Matrix Mitochondrial Membrane
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Butyryl-CoA Dehydrogenase Activity Protein Binding Isovaleryl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Leucine Catabolic Process Branched-chain Amino Acid Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways		G alpha (i) signalling events	Branched-chain amino acid catabolism
Drugs			Flavin adenine dinucleotide Coenzyme A persulfide
Diseases			Isovaleric acidemia (IVA)
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) FEV1 ( 30804560) Idiopathic pulmonary fibrosis ( 31710517) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 30804560) Malaria ( 31844061) Metabolic traits ( 21886157)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	4 interacting genes: ACTN3 GPSM3 MGAT5B PNMA1
Entrez ID		63940	3712
HPRD ID		13605	09516
Ensembl ID		ENSG00000213654	ENSG00000128928
Uniprot IDs		A0A024RCP6 Q9Y4H4	A0A0A0MT83 A0A0S2Z4K7 P26440
PDB IDs			1IVH
Enriched GO Terms of Interacting Partners?
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